Saeid Ghavami
Professor
University of Manitoba
Canada
Biography
Saeid Ghavami is Originally from Mashad, Khorasan, Iran, I have received my Bachelor of Chemistry degree from Shiraz University, Iran in 1989. I then completed my Master of Science and PhD degree in the Department of Clinical Biochemistry at Tarbiat Modarres University, Iran in 1996 and 2004 under the supervisions of Dr. Lotfi and Karami Tehrani respectively. Prior to joining to the Department of Human Anatomy and Cell Science University of Manitoba in October 2013 as an Assistant Professor/Principal Investigator, I worked as a postdoctoral fellow in the laboratory of Dr. Marek Los (CancerCare Manitoba), Dr. Andrew J. Halayko (Department of Physiology) and Dr. Ian MC Dixon (Department of Physiology) at University of Manitoba.
Research Interest
Currently my research focus is developing new therapeutic approaches in lung cancer, cardiopulmonary diseases, and infection disease based on modification of apoptosis, autophagy, and unfolded protein response(UPR)pathway. Mylong- term research plan will be built based on the following major topics: 1- Role of Autophagy and UPR in Regulation of Transforming Growth Factor beta 1 (TGF-ï¢1)-induced Epithelial Mesenchymal Transition (EMT) in Lung Cancer Model. 2-TargetingMevalonateCascadeasNewApproachforCancerTherapeuticStrategies: 3- Modulation of Virus Replication by Targeting Apoptosis/Autophagy/UPR.