7th international conference and Exhibition on Pharmacognosy, Phytochemistry and Natural Products
Osaka, Japan
Rifat Roshan
University of Karachi, Pakistan
Title: Evaluation of antitussive effect of wild strawberry on rats based on Traditional uses
Biography
Biography: Rifat Roshan
Abstract
Natural products have been used by human beings for treating different pathological conditions since the time immemorial. Numerous plants have been reported to have antitussive activity. The aim of our present study was to evaluate the antitussive effect of ethanolic extract of Fragaria nubicola (Hoof. f) L (Rosaceae) the doses of 100, 200 and 400 mg/kg in healthy albino rats. As we know that cough is a symptom and also a defensive reflex of removing the noxious, irritating substances and pathogens from larynx, trachea and bronchi . Cough is usually consider as the disease, related to lungs. Fragaria nubicola is commonly known as wild strawberry, found in wooded valleys at a height of 1500-3600m. Whole herb, fruits and leaves of Fragaria nubicola are used traditionally to treat different ailments. Dried roots, leaves and fresh fruits are useful in treating fever, cough and cold. Based on traditional use as antitussive agent the purpose of our study was to perform the antitussive effect on rats. In this study cough was induced by sulphur dioxide induction method. Animals were divided into eight groups of ten animals each and all the drugs were administered orally. Group I served as control group while group II served as standard. A dose-dependent inhibition of cough was observed for all extracts . At doses of 100, 200 and 400 mg/kg the extract was proved highly significant compared to standard . So it proves and supports traditional use of plant for relieving cough.