Elisabeth N.Barung
Health Polytechnic Manado, Indonesia
Title: Antypiretic Effect of Erythrina lithosperma Miq. leaves infusion on rats (Rattus norvegicus)
Biography
Biography: Elisabeth N.Barung
Abstract
Erythrina lithosperma Miq. leaves have been used as a traditional medicine to reduce fever. This study aimed to examine the antipyretic effect of Erythrina lithosperma Miq. leaves infusion on rats (Rattus norvegicus). This was a laboratory research with Pre and Post Test With Control Group design. The sample used was Erythrina lithosperma Miq.. leaves. Rats were febrile by injecting 20% ​​peptone solution intraperitoneally and expressed fever if the temperature rise was 1.5 °C from the initial temperature. The test was performed on selected white rats of 15 rats divided into 3 treatment groups: negative control group, positive control group, and Erythrina lithosperma Miq. leaves infusion group in which each group consisted of 5 rats. Temperature measurement was taken every 1 hour for 4 hours (t1, t2, t3, t4) after treatment. The data of rats body temperature analyzed descriptively and statistically by One Way Anova test. The results showed that Erythrina lithosperma Miq. leaves infusion had antipyretic effect on white rat (Rattus norvegicus) although not statistically significant.
