Divya Reddy
JSS Medical College, India
Title: Study of the diuretic activity in aqueous extract of roots of Anacyclus Pyrethrum in albino wistar rats
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Biography: Divya Reddy
Abstract
The aim of the study is to evaluate the diuretic activity of aqueous extract of roots of Anacyclus pyrethrum. Albino wistar rats weighing 200-250 gms of either sex were randomly selected from Central animal facility, JSS Medical College Mysuru. They were divided into 3 groups of 6 rats each (n=6).The animals were fasted overnight. Next day group 1which is control-received normal saline (25ml/kg.p.o), Group 2 which is standard-Furosemide 20mg/kg body weight. Group 3 which is test received 100mg/p.o Aqueous extract of roots of Anacyclus Pyrethrum. The experiment was carried out in a diuretic cage. The results, were analyzed by one Way Analysis Of Variance (ANOVA) .There was a significant diuretic activity compared to that of control. P value of less than 0.05 was considered significant.There was significant increase in urine volume by the aqueous extract of roots of Anacyclus Pyrethrum when compared to the control group.While the excretion of Urinary electrolyte concentration revealed a diluted urine in the test group signifying the diuretic activity of the extract. Aqueous extract of Anacylus pyrethrum have a significant diuretic activity in Albino wistar rats. Further tests are to isolate the active principles responsible for the activity suggested & also required to evaluate diuretic property in human subjects.
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