Hassan Abdalla Almahy Dafalla
Taif University, Kingdom of Saudi Arabia
Title: Chemical constituents of the leaves of Ficus nitida and their antimicrobial activity
Biography
Biography: Hassan Abdalla Almahy Dafalla
Abstract
The dichloromethane extract of the air-dried leaves of Ficus nitida belongs to the family Moraceae afforded lutein (1), β-sitosterol (2), stigmasterol (3), chlorophyll a (4), phytol (5), (E)-3-alkenoic acid (6), triglycerides, fatty alcohols, and fatty acids, while the twigs yielded saturated fatty acid ester. The structures of 1-5 on the basis of spectroscopic data such as IR, UV, 1H-NMR, 13C-NMR, COSY, HMQC, HMBC, DEPT and MS and confirmed by comparison data with those reported in the literature. The structure of 6 was elucidated by 1D and 2D NMR spectroscopy. However, bioactivity screening showed that the pure isolated compounds possessed activity on two species of bacteria Bacillus cereus NRRLUI-1447 and Pseudomonas aeruginosa UI-60690 and no activity against four species of fungi (Aspergillus ochraceus NRRL 398, Candida lipolytica ATCC 2075, Sacchromyces cereviseae NRRL 2034 and Sacchromyces lipolytica).